http://whatan00b.com/running-lamp-applications-using-nginx

This is what I used to setup a startup script for fastCGI to work with nginx. That allows me to run multiple wordpress blogs off my slicehost.

I basically followed the instructions here but adapted the proxy to my own needs.

http://wiki.list.org/display/DOC/Mailman+and+nginx

I couldn't get the ImageCache module for Drupal to work for the longest time because I didn't realize that the module came with a .htaccess file that pushes the image load back through Drupal to calculate the caching properly. Knowing this I was able to find this magical chunk for your nginx.conf (or your virtual host config). Slip this code in near the static serve file command

http://drupal.org/node/110224#comment-772191

# imagecache needs to have php read any files that it's planning to manipulate
location ^~ /sites/default/files/imagecache/ {
     index  index.php index.html;
     # assume a clean URL is requested, and rewrite to index.php                                                                 
      if (!-e $request_filename) {
          rewrite  ^/(.*)$  /index.php?q=$1  last;
          break;
      }
}

# serve static files directly
location ~* ^.+.(jpg|jpeg|gif|css|png|js|ico)$ {
    access_log        off;
    expires           30d;
}